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新冠mRNA疫苗竞速赛:Moderna已经展开人体试验

文/贝壳社 2020-03-20 11:26:43 来源:中国网大连娱网棋牌 频道

全球新冠疫苗研发消息盘点

编辑 | 鹿柴

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其实在这场新冠疫苗研发竞速赛中,跑的最快的最吸引人关注的走的都是核酸路线波克棋牌下载,Moderna,BioNTech和CureVac,包括中国的斯微生物。据悉,斯微生物和中疾控及同济大学附属东方医院研发的mRNA疫苗据悉已启动灵长类动物毒理和药效预实验,预计四月中旬临床试验,病毒样颗粒(VLP)疫苗,小鼠免疫实验已产生特异性抗体。

核酸疫苗是全世界都在积极探索的疫苗研发新技术,但是目前全球还没有人用疫苗上市。波克棋牌下载对于世界来说,本次新冠疫情毋庸置疑是场大灾难,但是对于mRNA行业来说,应该是一个检验和证明的良好机会。

CIQIAN,SHIJIE网上棋牌中心ZUZHICENGYUJI,XINXINGGUANZHUANGBINGDUYIMIAOYOUWANGZAI18GEYUENEIZHUNBEIJIUXU,NEIME,HAOCHENG“mRNASANDACHUANQIGONGSI”DEModerna,BioNTechHECureVacXINGUANYIMIAOYANFAJINZHANDAODIRUHENI?JIEXIALAI,WOMENJIUYIQILAIKANKANBA。

1、Moderna:进展速度最快,首例新冠疫苗人体试验已开展

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没想到3月16日,Moderna生产的mRNA-1273新冠病毒候选疫苗即迎来了首例人体试验。不过,与过往的疫苗研发过程不同的地方在于,mRNA-1273跳过了动物试验,直接开展人体测试。43岁的詹妮弗·哈勒是第一位在西雅图凯撒医院接种实验疫苗的志愿者,陆续将有45名年轻健康的志愿者注射不同剂量的试剂。据了解,测试疫苗本身并不含病毒,志愿者不会有感染风险,第一阶段实验只为验证疫苗的安全性和副作用。

詹妮弗接种疫苗 图源网络

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不过也有评论表示,跳过动物实验展开人体疫苗测试,这一模式正在打破人类研制疫苗的常规思维。这不仅存在伦理问题,更让实验者面临更多未知的危害,疫苗的安全性未必得到充分保障。

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2、BioNTech:引入辉瑞、复星,预计四月份之前进入临床

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该公司新研发的一种名为BNT162的疫苗表现良好,将在获得相关部门批准后,从4月底起开展全球临床试验,范围包括欧洲、中国和美国。

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3、CureVac:想“低调”都不行,因为疫苗遭德国和美国“争抢”

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